Salihu Abdullahi Kiyawa, Mukhtar, Z. G, Ibrahim, Y. I

The   study   was   conducted   to   evaluate the   antioxidant   and antipyretic activity of Adansonia digitata (African Baobab) fruit, leaf and bark extracts.  Antioxidant activity of plant part extracts were determined by free radical   Diphenylpicrylhydrazyl (DPPH) assay   while   the   antipyretic activity was assessed using experimental animals. Antioxidant activity of leaf extract showed a value of 13.40±0.77, bark extract 29.23±1.69 while fruit extract gave a value of 39.21±2.26. For the Antipyretic activity results, the average temperature of Albino Wister rats was   21.65±0.96 oC   before   fever   inducement   and 30.64±1.37 oC   after inducement. Following the administration of the leaf extract (400 mg/kg and 800 mg/kg), bark   extract (400 mg/kg   and   800 mg/kg) and   fruit   extract (400 mg/kg and 800 mg/kg), the body temperature of the albino rats fell to25.96±1.16 oC vs.   25.28±1.13 oC, 26.06±1.17 oC vs. 25.02±1.12 oC, and 25.78±1.15 oC vs. 24.30±1.09 oC respectively. The   results   showed   that   the   fruit   extract   has   a   higher antioxidant and antipyretic activity than bark and leaf extracts.


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