Abstract

Iram Ayoob, Mohd Akbar Khuroo, Masood ur Rahman, Khursheed Ahmad Bhat, Shahid Banday

Rheum emodi (Polygonate) commonly known as ‘‘Pambchallan’’(in Kashmir) is a medicinally important plant showing a wide range of biological activities. Phytochemical investigation of the roots of this plant yielded six compounds i.e. Chrysophanol, emodin, noreugenin, Physcion, aloe-emodin glycoside, and Chrysin. All the isolated compounds were envisaged for bio evaluation (antioxidant and antimicrobial activity). Among all tested isolates, compounds 13 and were found to be better antioxidants and with respect to antimicrobial screening, varied activity was demonstrated by all the six compounds against bacterial and fungal pathogens. Compounds 1and 5 were found to be active against both fungal strains. Compounds 2 and 3 were active against single bacterial strain E.coli while as compound 6 was found to be potent against bacterial pathogen E.coli and fungal pathogen A. fumigatus.

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