Minhajur Rahman, Nayema Ferdous, ANM Alamgir

Melastoma malabathricum (L.) Smith; a naturally growing plant of Bangladesh is investigated in the present experiment for its secondary metabolites, cytotoxic and antibacterial activities. Among the secondary metabolites alkaloid, flavonoid, sterol, tannin and glycoside found to be present while saponin is absent in its leaf. Ethanolic extract of M. malabathricum leaf showed significant cytotoxicity with the LC50 value of 19.38μg/ml.  In the antibacterial screening, the highest zone of inhibition record was 8 mm (at 100mg/ml) and the lowest was 5 mm (at 50mg/ml). These significant cytotoxic and antibacterial activities also corroborate its ethno-medicinal practices.


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